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Charcot-Marie-Tooth Disease (CMT)

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What is it?

Charcot-Marie-Tooth disease is a group of inherited disorders that affect the peripheral nerves, causing muscle weakness, atrophy, and sensory loss. It is one of the most common inherited neurological disorders.

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What are the symptoms?

  • Muscle weakness, especially in the feet, legs, and hands

  • Numbness or loss of sensation in the arms and legs

  • High arches or flat feet

  • Foot drop (difficulty lifting the foot)

  • Difficulty with fine motor skills (e.g., buttoning a shirt)

  • Pain and cramps in muscles

  • Loss of reflexes

What else could it be? (Differential diagnosis)

  • Polio

  • Peripheral neuropathy

  • Multiple sclerosis (MS)

  • Muscular dystrophy

What are the aggravating factors?

  • Family history (genetic inheritance)

  • Physical inactivity (can worsen muscle weakness)

  • Injury or trauma to the nerves

What types of food are helpful?

  • High-protein diet: For muscle support (found in chicken, fish, beans, and tofu).

  • Healthy fats: Omega-3 fatty acids for nerve health (found in fish, flaxseeds, and walnuts).

  • Antioxidant-rich foods: To support nerve function (found in berries, spinach, and kale).

Sample Recipe: Grilled Salmon with Spinach Salad

  • Ingredients: Salmon, spinach, olive oil, lemon juice, almonds.

  • Directions: Grill salmon and serve with a spinach salad dressed in olive oil and lemon juice for a nutrient-dense meal.

What are the traditional treatments?

  • Physical therapy: To improve strength and mobility.

  • Orthopedic devices: Braces or splints to assist with walking.

  • Pain management: Over-the-counter pain relievers and anticonvulsants to manage nerve pain.

  • Surgery: In some cases, surgery to correct foot deformities.

What are the natural and alternative treatments?

  • Alpha-lipoic acid: An antioxidant that may help protect nerve cells.

  • Acupuncture: Some people find relief from pain and muscle spasms through acupuncture.

  • Exercise: Regular low-impact exercises like swimming and cycling may help maintain      muscle strength and improve mobility.

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