Cushing's Disease

What is it?

Cushing’s disease is a condition caused by an overproduction of cortisol, a hormone that regulates various functions in the body. It is most often due to a pituitary tumor that stimulates excess cortisol release.

What are the symptoms?

Weight gain, especially around the face and abdomen
Thin skin and easy bruising
Muscle weakness
High blood pressure
Diabetes or increased blood sugar
Mood swings and irritability
Fatigue
Irregular periods in women

What else could it be? (Differential diagnosis)

Other causes of hypercortisolism (e.g., adrenal tumors)
Polycythemia vera
Hypothyroidism

What are the aggravating factors?

Prolonged use of corticosteroid medications
Pituitary tumors or abnormalities
Genetic predispositions (e.g., familial Cushing's)

What types of food are helpful?

Low-sodium diet: To manage high blood pressure and water retention.
High-protein foods: To support muscle mass (e.g., lean meats, eggs).
Low-glycemic foods: To manage blood sugar levels (e.g., whole grains, legumes).

Sample Recipe: Egg and Spinach Scramble

Ingredients: Eggs, spinach, garlic, olive oil.
Directions: Scramble eggs with sautéed spinach for a protein- and fiber-rich breakfast.

What are the traditional treatments?

Surgery: To remove pituitary tumors or adrenal glands in some cases.
Medications: Such as cortisol blockers or steroid-sparing drugs.
Radiation therapy: For inoperable pituitary tumors.

What are the natural and alternative treatments?

Vitamin C: Known to support adrenal function.
Licorice: In small doses, may help manage cortisol levels.
Adrenal tonics: Herbal blends designed to support adrenal glands, like ashwagandha.