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Fibrodysplasia Ossificans Progressiva (FOP)
What is it?
Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder where soft tissues such as muscles, tendons, and ligaments progressively turn into bone. This results in severe limitations in movement and may cause disability over time.

What are the symptoms?
Abnormal bone growth in muscles, tendons, and ligaments
Joint stiffness and immobility
Progressive loss of movement as bones form in soft tissue
Deformities due to bone growth
What else could it be? (Differential diagnosis)
Myositis ossificans (benign bone formation after injury)
Other connective tissue disorders
Osteogenesis imperfecta
What are the aggravating factors?
Trauma or injury to soft tissues (can trigger flare-ups)
Viral infections (may exacerbate bone growth)
Hormonal changes (e.g., puberty or pregnancy)
What types of food are helpful?
Calcium and Vitamin D: To support bone health, include dairy products, leafy greens, and fortified foods.
Anti-inflammatory foods: Foods like fatty fish, turmeric, and leafy vegetables can help reduce inflammation.
Sample Recipe: Grilled Salmon with Steamed Kale
Ingredients: Salmon, kale, olive oil, garlic, lemon.
Directions: Grill salmon with lemon, olive oil, and garlic. Steam kale and serve as a side.
What are the traditional treatments?
No cure: There is no known cure, but management focuses on preventing flare-ups and improving quality of life.
Pain management: Nonsteroidal anti-inflammatory drugs (NSAIDs) may be used to manage pain.
Physical therapy: To maintain mobility as much as possible.
What are the natural and alternative treatments?
Turmeric and ginger: Both have natural anti-inflammatory properties and may help reduce flare-ups.
Acupuncture: Some patients report that acupuncture helps with pain management.
Omega-3 fatty acids: Fish oil supplements may help manage inflammation and pain.
Medical Disclaimer: The information provided on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you may have regarding a medical condition. Reliance on any information provided on this website is solely at your own risk.