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Focal Segmental Glomerulosclerosis (FSGS)

What is it?

Focal Segmental Glomerulosclerosis (FSGS) is a disease of the kidneys where some of the kidney’s filtering units (glomeruli) become scarred. It can lead to kidney failure over time if not treated.

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What are the symptoms?

  • Swelling in the legs, ankles, and feet (edema)

  • Foamy urine (due to protein leakage)

  • High blood pressure

  • Fatigue

  • Decreased urine output

What else could it be? (Differential diagnosis)

  • Minimal change disease (another kidney condition causing protein loss)

  • Diabetic nephropathy

  • Hypertensive nephropathy

  • Lupus nephritis

What are the aggravating factors?

  • Poor management of underlying conditions (e.g., hypertension, diabetes)

  • Certain medications (e.g., NSAIDs)

  • Infections or diseases that stress the kidneys

What types of food are helpful?

  • Low-sodium diet: Helps manage swelling and high blood pressure.

  • Adequate protein: But controlled protein intake to avoid kidney strain.

  • Omega-3 fatty acids: Found in fish, flaxseed, and walnuts, may help manage inflammation.

Sample Recipe: Grilled Fish with Steamed Vegetables

  • Ingredients: Salmon, olive oil, garlic, broccoli, zucchini.

  • Directions: Grill salmon with olive oil and garlic, then steam vegetables as a side dish.

What are the traditional treatments?

  • Corticosteroids: To reduce inflammation and protein loss in urine.

  • Immunosuppressive drugs: Such as cyclosporine or mycophenolate mofetil.

  • Angiotensin-converting enzyme (ACE) inhibitors: To manage blood pressure and reduce protein leakage.

What are the natural and alternative treatments?

  • Omega-3 supplements: Some studies suggest omega-3 fatty acids may reduce kidney inflammation.

  • Turmeric: Curcumin in turmeric may help manage inflammation in kidney diseases.

  • Herbal teas: Dandelion root and nettle may promote kidney health.

Medical Disclaimer: The information provided on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you may have regarding a medical condition. Reliance on any information provided on this website is solely at your own risk.

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