Granulomatosis with Polyangiitis (GPA)

What is it?

GPA is a rare autoimmune disease that causes inflammation of the blood vessels (vasculitis), which affects various organs, including the kidneys, lungs, and sinuses.

What are the symptoms?

Sinus pain or congestion
Coughing up blood
Shortness of breath
Fever and fatigue
Kidney problems (dark urine, swelling)
Skin rashes or sores

What else could it be? (Differential diagnosis)

Other types of vasculitis (e.g., microscopic polyangiitis, Takayasu arteritis)
Chronic sinus infections
Autoimmune diseases like lupus or rheumatoid arthritis

What are the aggravating factors?

Genetic predisposition
Smoking may worsen the disease.
Environmental triggers like infections.

What types of food are helpful?

Anti-inflammatory diet: Focus on omega-3 fatty acids, such as fish, flaxseeds, and walnuts.
Adequate protein: To help with tissue repair and immune function (e.g., chicken, beans).
Vitamin D and calcium: Especially if taking corticosteroids, which can affect bone health.

Sample Recipe: Baked Salmon with Roasted Vegetables

Ingredients: Salmon fillet, carrots, zucchini, olive oil, lemon.
Directions: Roast salmon and vegetables with olive oil and lemon for a nutrient-dense, anti-inflammatory meal.

What are the traditional treatments?

Immunosuppressive drugs: Such as cyclophosphamide or methotrexate to control inflammation.
Corticosteroids: To reduce inflammation and manage symptoms.
Plasmapheresis: In severe cases, to remove harmful antibodies from the blood.

What are the natural and alternative treatments?

Turmeric and ginger: May help reduce inflammation.
Vitamin C: Supports the immune system and helps with skin and tissue repair.
Probiotics: To support gut health and immune function.

Medical Disclaimer: The information provided on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you may have regarding a medical condition. Reliance on any information provided on this website is solely at your own risk.