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Lynch Syndrome

What is it?

Lynch syndrome, also known as hereditary non-polyposis colorectal cancer (HNPCC), is a genetic condition that increases the risk of colon cancer and other types of cancer due to inherited mutations in genes that repair DNA.

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What are the symptoms?

  • Family history of colorectal cancer or other cancers (e.g., uterine, ovarian, stomach, small bowel)

  • Early-onset colon cancer (before age 50)

  • Multiple family members diagnosed with cancer

  • Sometimes, no immediate symptoms are present until cancer develops.

What else could it be? (Differential diagnosis)

  • Familial adenomatous polyposis (FAP)

  • Inherited polyposis syndromes

  • Hereditary breast and ovarian cancer syndrome

  • Non-genetic (sporadic) cases of colorectal cancer

What are the aggravating factors?

  • Family history of Lynch syndrome or cancers

  • Inheritance of a defective gene from a parent

  • Age (risk increases as individuals age)

What types of food are helpful?

  • Fiber-rich diet: To promote gut health and regular bowel movements, which may help reduce colon cancer risk.

  • Antioxidant-rich foods: Increase intake of fruits, vegetables, and whole grains.

  • Limit red meat and processed foods: Some studies suggest a higher risk of colon cancer from these foods.

Sample Recipe: Vegetable Stir-Fry with Brown Rice

  • Ingredients: Mixed vegetables (broccoli, bell peppers, carrots), tofu or lean protein, brown rice, olive oil, soy sauce.

  • Directions: Stir-fry vegetables and tofu in olive oil and serve with brown rice for a fiber-rich meal.

What are the traditional treatments?

  • Genetic testing: To confirm the presence of Lynch syndrome mutations.

  • Regular screening: Colonoscopy and other cancer screenings, starting earlier than the general population (e.g., age 20-25).

  • Prophylactic surgery: Removal of at-risk tissues, such as colectomy (colon removal) or hysterectomy, to reduce cancer risk.

  • Chemotherapy: If cancer develops, chemotherapy may be used based on the type and stage of cancer.

What are the natural and alternative treatments?

  • Flaxseed: Contains lignans and fiber, which may reduce cancer risk.

  • Green tea: Studies have suggested that green tea polyphenols might lower the risk of colon cancer.

  • Curcumin: Found in turmeric, curcumin may help prevent cancer cell growth.

Medical Disclaimer: The information provided on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you may have regarding a medical condition. Reliance on any information provided on this website is solely at your own risk.

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