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Primary Biliary Cirrhosis

What is it?

Primary biliary cirrhosis (PBC), now more commonly called primary biliary cholangitis (PBC), is a chronic disease that damages the bile ducts in the liver. This impairs bile flow, leading to liver damage, scarring (cirrhosis), and, over time, liver failure.

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What are the symptoms?

  • Fatigue

  • Itchy skin (pruritus)

  • Jaundice (yellowing of the skin and eyes)

  • Dry eyes or mouth

  • Abdominal discomfort

  • Dark-colored urine

What else could it be? (Differential diagnosis)

  • Hepatitis

  • Cholestasis

  • Autoimmune hepatitis

  • Liver cancer

What are the aggravating factors?

  • Autoimmune diseases: PBC is an autoimmune disorder, and other autoimmune diseases (e.g., thyroid disease, rheumatoid arthritis) may co-occur.

  • Genetics: A family history of PBC increases risk.

  • Gender: Women are more likely to develop PBC than men.

What types of food are helpful?

  • Low-sodium diet: To help manage fluid retention, particularly in advanced stages of cirrhosis.

  • High-fiber foods: Fruits, vegetables, and whole grains are important for overall health.

  • Omega-3 fatty acids: Fatty fish (salmon, mackerel) and flaxseed can help reduce inflammation.

Sample Recipe: Salmon with Lemon and Dill

  • Ingredients: Salmon fillets, lemon, dill, olive oil, garlic.

  • Directions: Roast the salmon with lemon, dill, and garlic for a simple anti-inflammatory dish.

What are the traditional treatments?

Ursodeoxycholic acid (UDCA): A medication that can slow the progression of the disease by improving bile flow.

Cholestyramine: To alleviate itching.

Liver transplantation: In severe cases, a liver transplant may be necessary.

What are the natural and alternative treatments?

  • Milk thistle: An herb that some studies suggest may have liver-protective effects.

  • Turmeric: Curcumin, the active compound in turmeric, is known for its anti-inflammatory properties.

Medical Disclaimer: The information provided on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you may have regarding a medical condition. Reliance on any information provided on this website is solely at your own risk.

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