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Primary Biliary Cirrhosis
What is it?
Primary biliary cirrhosis (PBC), now more commonly called primary biliary cholangitis (PBC), is a chronic disease that damages the bile ducts in the liver. This impairs bile flow, leading to liver damage, scarring (cirrhosis), and, over time, liver failure.

What are the symptoms?
Fatigue
Itchy skin (pruritus)
Jaundice (yellowing of the skin and eyes)
Dry eyes or mouth
Abdominal discomfort
Dark-colored urine
What else could it be? (Differential diagnosis)
Hepatitis
Cholestasis
Autoimmune hepatitis
Liver cancer
What are the aggravating factors?
Autoimmune diseases: PBC is an autoimmune disorder, and other autoimmune diseases (e.g., thyroid disease, rheumatoid arthritis) may co-occur.
Genetics: A family history of PBC increases risk.
Gender: Women are more likely to develop PBC than men.
What types of food are helpful?
Low-sodium diet: To help manage fluid retention, particularly in advanced stages of cirrhosis.
High-fiber foods: Fruits, vegetables, and whole grains are important for overall health.
Omega-3 fatty acids: Fatty fish (salmon, mackerel) and flaxseed can help reduce inflammation.
Sample Recipe: Salmon with Lemon and Dill
Ingredients: Salmon fillets, lemon, dill, olive oil, garlic.
Directions: Roast the salmon with lemon, dill, and garlic for a simple anti-inflammatory dish.
What are the traditional treatments?
Ursodeoxycholic acid (UDCA): A medication that can slow the progression of the disease by improving bile flow.
Cholestyramine: To alleviate itching.
Liver transplantation: In severe cases, a liver transplant may be necessary.
What are the natural and alternative treatments?
Milk thistle: An herb that some studies suggest may have liver-protective effects.
Turmeric: Curcumin, the active compound in turmeric, is known for its anti-inflammatory properties.
Medical Disclaimer: The information provided on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you may have regarding a medical condition. Reliance on any information provided on this website is solely at your own risk.