Protein-Losing Enteropathy (PLE)

What is it?

Protein-losing enteropathy (PLE) refers to a condition in which there is an abnormal loss of protein from the gastrointestinal tract. This can occur due to various underlying causes, including heart disease, liver disease, and certain gastrointestinal disorders.

What are the symptoms?

Swelling (edema), especially in the legs and abdomen
Diarrhea or steatorrhea (fatty stools)
Fatigue
Weight loss
Protein deficiency symptoms like hair thinning, poor wound healing, and weakness

What else could it be? (Differential diagnosis)

Celiac disease
Inflammatory bowel disease (IBD)
Heart failure
Liver cirrhosis

What are the aggravating factors?

Chronic diseases: Conditions like congestive heart failure and cirrhosis can exacerbate PLE.
Gastrointestinal conditions: Disorders that affect the intestines or cause inflammation can trigger PLE.

What types of food are helpful?

High-protein diet: Include protein-rich foods such as lean meats, fish, eggs, and legumes.
Low-sodium foods: To help reduce edema and fluid retention.
Fiber: For better digestion and to manage diarrhea, focus on soluble fiber like oats and bananas.

Sample Recipe: Grilled Chicken with Quinoa and Spinach

Ingredients: Chicken breast, quinoa, spinach, olive oil, garlic.
Directions: Grill chicken and serve with quinoa and sautéed spinach for a balanced, high-protein meal.

What are the traditional treatments?

Management of underlying conditions: Treating heart disease, liver disease, or other contributing factors.
Dietary management: High-protein and low-sodium diets may help manage symptoms.
Diuretics: To control fluid retention and swelling.

What are the natural and alternative treatments?

Probiotics: These may help balance gut health and reduce inflammation.
Herbal teas: Peppermint or ginger tea may soothe digestive issues associated with PLE.

Medical Disclaimer: The information provided on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you may have regarding a medical condition. Reliance on any information provided on this website is solely at your own risk.