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Zollinger-Ellison Syndrome

What is it?

Zollinger-Ellison syndrome is a rare condition where tumors in the pancreas or duodenum cause an overproduction of stomach acid, leading to peptic ulcers and other gastrointestinal issues.

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What are the symptoms?

  • Severe peptic ulcers

  • Gastric reflux or heartburn

  • Diarrhea

  • Abdominal pain

  • Nausea

  • Weight loss

What else could it be? (Differential diagnosis)

  • Peptic ulcer disease: Ulcers in the stomach or duodenum caused by excess acid production.

  • Gastroesophageal reflux disease (GERD): Can cause symptoms of heartburn and reflux.

  • Gastrinoma: Tumors producing excess gastric acid, leading to similar symptoms.

What are the aggravating factors?

  • Excessive stomach acid production: The key characteristic of the condition.

  • Certain foods: Spicy, fatty, or acidic foods can worsen symptoms.

  • Stress: May increase acid production and aggravate symptoms.

What types of food are helpful?

  • Low-acid foods: Avoid citrus, tomatoes, and spicy foods that can exacerbate symptoms.

  • Small, frequent meals: To reduce the load on the stomach and prevent excess acid production.

  • Increased fiber: High-fiber foods, such as vegetables and whole grains, can aid digestion.

What are the traditional treatments?

  • Proton pump inhibitors (PPIs): To reduce stomach acid and promote healing of ulcers.

  • Surgical removal of tumors: In some cases, tumors causing the excess acid production may be surgically removed.

  • Chemotherapy or radiation: For cancerous tumors.

  • Antacids: To neutralize stomach acid and reduce symptoms.

What are the natural and alternative treatments?

  • Slippery elm: Known to soothe and protect the lining of the stomach.

  • Aloe vera juice: Can have a soothing effect on the digestive tract.

  • Chamomile tea: May help with stomach inflammation and acid reflux.

Medical Disclaimer: The information provided on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you may have regarding a medical condition. Reliance on any information provided on this website is solely at your own risk.

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